Actinium-225 (Ac-225) is a radioactive isotope that emits alpha particles, which are highly effective at killing cancer cells. PSMA (Prostate-Specific Membrane Antigen) is a protein found on the surface of prostate cancer cells.
1. High-energy alpha particles effectively kill tumor cells.
2. Short range (50-100 μm) in tissues minimizes damage to surrounding healthy cells.
3. Potential for improved efficacy compared to beta-emitting isotopes (Lutetium-177).
1. Dry Mouth
2. Fatigue
3. Nausea and vomiting
4. Bone marrow suppression
5. Kidney damage (Rare)
It’s a targeted radiation therapy using Actinium-225 to treat advanced prostate cancer by targeting PSMA on tumor cells.
The Actinium-225 isotope binds to PSMA on prostate cancer cells, delivering radiation to destroy tumors effectively
Yes, it’s generally safe, but side effects like fatigue, dry mouth, or nausea may occur.
The treatment typically involves a single injection and takes around 1-2 hours, including preparation and imaging.
Disclaimer: This information is intended for general knowledge and informational purposes only, and does not constitute medical advice. Please consult with a qualified healthcare professional for any medical concerns or treatment decisions.
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